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NINSERT focuses on developing selective nitrogen insertion techniques in organic chemistry to enhance the synthesis of nitrogen-containing compounds. This project aims to improve drug development processes by enabling late-stage modifications of compounds, particularly those with heterocyclic structures commonly found…
NINSERT constitutes a program to embark on selective and mild nitrogen insertions, both within and beyond carbonyl chemistry.
Reagent development, catalyst design, and synergistic effects will be evaluated to provide a platform for late-stage skeletal editing, an area that has been recently brought to the forefront of organic chemistry.
With a primary emphasis on heterocyclic motifs, commonly encountered in natural products and drug candidates, NINSERT offers a powerful tool to streamline future…
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