CORDIS Project
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This project investigates the role of long non-coding RNAs in age-related heart failure with preserved ejection fraction (HFpEF). It aims to uncover molecular mechanisms of cardiac ageing and intercellular communication, focusing on specific lncRNAs that may serve as potential therapeutic targets for improving heart fu…
Life expectancy in the European Union is rising and the prevalence of age-induced cardiovascular disease increases concomitantly.
The main clinical presentation of age-induced cardiovascular disease is heart failure with preserved ejection fraction (HFpEF). HFpEF is a complex disease involving different cell types and mechanisms that contribute to impaired relaxation of cardiomyocytes.
Currently there is no appropriate treatment for HFpEF.
This proposal aims to better understand the molecular me…
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