CORDIS Project
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This project focuses on the study and development of small-ring propellanes, which are important for creating valuable molecules in pharmaceuticals and materials science. It aims to enhance understanding of their unique reactivity and develop new synthetic methods for accessing complex chiral compounds.
Propellanes are molecules of high importance as precursors to valuable cage molecules in pharmaceutical and materials research.
For smaller-ring propellanes, ubiquitous reactivity can be displayed towards anions, radicals, and cations; however, the theoretical basis for this unusual behaviour has only recently emerged, which is based on the ability of small ring propellanes to delocalise electron density away from the electron-rich central C–C bond onto the peripheral carbon atom p orbitals both…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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