CORDIS Project
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The NeuroTRACK project investigates the progression of neurodegenerative diseases by studying how protein misfolding spreads through the brain's neural networks. Utilizing advanced imaging techniques, it aims to develop tools for early detection and monitoring of diseases like frontotemporal lobar degeneration.
Current knowledge of neurodegenerative diseases is limited by poor understanding of how they progress through the central nervous system (CNS).
It has recently been hypothesized that clinical progression in these conditions involves the systematic spreading of protein misfolding along neuronal pathways.
Protein aggregates would trigger misfolding of adjacent homologue proteins in newly-affected regions, and this would propagate in a “prion-like” fashion across anatomical connections.
This propos…
OSPEDALE SAN RAFFAELE SRL
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