CORDIS Project
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This project develops in-vivo mouse models to study spinal cord circuitry and hereditary neurological disorders. It focuses on refining experimental preparations to analyze synaptic connections and plasticity in transgenic mice with specific genetic mutations.
The development of transgenic mice affecting development of spinal cord circuitry or mimicking hereditary neurological motor disorders has necessitated the development of in-vivo adult mouse preparations for electrophysiology to bridge molecular biology with the pathophysiology of phenotypes.
The first goal is the development and refinement of a “mouse in-vivo spinal cord preparation” for intracellular recordings and analysis of spinal circuitry in “acute experiments” and a preparation for chron…
KOBENHAVNS UNIVERSITET
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