CORDIS Project
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This project investigates the role of neuroinflammation in Alzheimer's and Parkinson's diseases by analyzing changes in protein signaling in response to inflammatory stress. Using advanced proteomics and cell models, it aims to uncover cellular mechanisms that could lead to new therapeutic strategies for these neurodeg…
Alzheimer’s (AD) and Parkinson’s disease (PD) are prevalent neurodegenerative diseases, but their underlying mechanisms remain poorly understood.
Emerging evidence suggests that neuroinflammation, characterized by the release of pro-inflammatory cytokines like IL-1β, TNF-α, and INF-γ, plays a pivotal role in these diseases, challenging the conventional focus on protein aggregates (Aβ, αSyn).
In AD, it has been shown that elevated IL-1β levels induce the translocation of NEDD8 from the nucleus to…
KOBENHAVNS UNIVERSITET
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