CORDIS Project
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This project investigates how aging affects nerve density and vascular interactions in the heart, which may lead to cardiovascular issues. It aims to understand the mechanisms behind these changes and their implications for heart health in the elderly, focusing on the role of specific proteins and cellular interactions…
Aging is a major risk factor for impaired cardiovascular health.
The aging myocardium is characterized by endothelial cell dysfunction, diastolic and systolic impairment, increased hypertrophy and fibrosis and electrophysiological alterations that predisposes the elderly to arrhythmic risk.
The mechanism of age-associated pathophysiological alterations are incompletely understood.
In preliminary data, we report that aging is associated with a decline in axon density in the heart.
Since vessels a…
JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN
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