CORDIS Project
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This project investigates the neural mechanisms regulating energy expenditure and body weight, focusing on the connection between the ventromedial hypothalamus and brown adipose tissue. It aims to clarify the role of serotonin in this circuit, potentially leading to new insights in obesity treatment.
Obesity is now a global epidemic with a significant and deleterious impact on human health.
My career aim is to clarify the neural underpinnings of energy expenditure (EE) given that this makes a significant contribution to body weight.
During my early career, I discovered a circuit linking the ventromedial hypothalamus (VMH) to brown adipose tissue (BAT) and inducing thermogenic beige (browning) white adipose tissue (WAT), regulating EE.
Moreover, I found that the VMH-BAT axis is utilized by es…
THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN
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