CORDIS Project
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This project investigates the mechanisms of cell communication in neurons, focusing on how signaling pathways are affected in neurodegenerative diseases like Amyotrophic Lateral Sclerosis. By creating specialized platforms and using advanced imaging techniques, it aims to uncover vital factors for neuron survival and s…
In order to survive and maintain normal function, the cell depends on a dynamic system of spatial specificity and fidelity of signaling pathways that can respond to both internal and external changes over space and time.
This cell-cell communication is mediated by ligand-receptor mechanisms.
In the case of highly polarized cells such as neurons trafficking mechanisms mediated by motor proteins are used to achieve precise signal targeting.
Alterations in the trafficking machinery may results in i…
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