CORDIS Project
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This project aims to understand protein interactions at synapses in the brain, particularly focusing on the postsynaptic density. It will develop innovative tools to manipulate these interactions, enhancing our understanding of synaptic plasticity and its implications for learning and memory.
Complex dynamic protein-protein interactions are the base of protein-based networks in cells.
Among them, the synaptic connection between two neurons is one of the most challenging.
The postsynaptic density (PSD) at excitatory synapses in the brain is a prototypical example of protein-based network whose nanoscale structure and composition determines cellular function.
Moreover, dynamic regulation of PSD composition and receptor movement into or out of the PSD is the base of current molecular th…
UNIVERSITE VICTOR SEGALEN BORDEAUX II
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