CORDIS Project
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The project investigates the role of the protein alpha-synuclein in neurodegenerative diseases, particularly Parkinson's Disease. It aims to develop a network of researchers to study the protein's conformations and mechanisms of toxicity using various experimental models.
Parkinson’s Disease (PD) is the second most common neurodegenerative disorder.
It is characterized pathologically by the accumulation of aggregated conformations of the presynaptic protein alpha-synuclein (ASYN) in cytoplasmic inclusions termed Lewy Bodies (LBs).
Furthermore, aberrant aggregated species of ASYN accumulate in various disease states, such as Multiple System Atrophy, Diffuse LB Disease, LB Variant of Alzheimer’s Disease and others, collectively termed synucleinopathies.
Point mutat…
EBERHARD KARLS UNIVERSITAET TUEBINGEN
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
BIOMEDICAL RESEARCH FOUNDATION, ACADEMY OF ATHENS
Greece, Athina
Type: Research institute
Activity type: Research Organisations
SME: No
Denmark, Aarhus C
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Sweden, LUND
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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