CORDIS Project
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This project investigates the metabolic interactions between oligodendrocytes and other glial cells during the life cycle of myelin, focusing on how lipoproteins regulate lipid metabolism in the central nervous system. It aims to understand these processes in the context of aging and neurodegenerative diseases, potenti…
Myelin is an abundant, lipid-rich membrane structure formed by oligodendrocytes, each of which extends numerous processes to form distinct myelin internode segments along axons, thereby increasing neural processing speed and energetic efficiency.
Myelin undergoes a life cycle with three fundamental distinct phases of metabolism, starting with an anabolic phase of early postnatal myelin development, followed by a homeostatic, adult state, in which turnover is low, and ending with a catabolic, mye…
TECHNISCHE UNIVERSITAET MUENCHEN
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