CORDIS Project
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This project investigates the interactions between pancreatic ductal adenocarcinoma and nerve cells to identify new therapeutic targets. Using advanced transcriptomics, it aims to uncover the cellular pathways involved in nerve invasion by cancer cells, potentially leading to innovative treatment strategies for this ag…
Pancreatic ductal adenocarcinoma (PDAC) is an exceptionally aggressive cancer with a 5-year survival rate below 10%.
It is resistant to traditional treatments and unresponsive to immunotherapy.
New insights into the biology of PDAC are needed to identify novel therapeutic targets.
Nerve invasion, defined as the presence of cancer cells along nerves and within different layers of nerve fibres, is a hallmark feature of PDAC.
Patients that show signs of nerve invasion have a worse prognosis, higher…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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