CORDIS Project
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This project explores the mechanisms of nuclear envelope remodeling during mitosis in the fission yeast Schizosaccharomyces japonicus. By investigating the roles of specific proteins and kinases, it aims to provide insights into mitotic processes that are relevant to understanding cell division and potential cancer mec…
Mitosis ensures faithful inheritance of genetic material in proliferating eukaryotic cells.
Cellular genome is compartmentalized inside the nucleus, which is delimited by the double-membrane nuclear envelope (NE).
The NE must be restructured during mitosis to allow chromosome segregation by the mitotic spindle and formation of the daughter nuclei.
Eukaryotes perform this task using diverse approaches, ranging from fully “open” to fully “closed” mitosis depending on whether and when the NE breaks…
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United Kingdom, London
Type: Research institute
Activity type: Research Organisations
SME: No
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