CORDIS Project
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This project aims to develop a sophisticated in vitro model of the kidney using bioprinting technologies and induced pluripotent stem cells. The goal is to create a vascularized kidney organoid that mimics natural function, potentially paving the way for new therapies for chronic kidney disease.
Chronic kidney disease (CKD) results in loss of kidney function in patients, ultimately requiring organ transplant.
Critical organ shortage and organ rejection after transplant make extended dialysis inevitable and the only therapy available.
To exacerbate this problem, the incidence of CKD is increasing worldwide, with >14% of the general population affected.
Hence, there is an urgent need for novel therapies.
Induced pluripotent stem cells have been used to create kidney organoids representing…
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