CORDIS Project
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The NEPHIMLEI project investigates the neuroendocrine system of the sand fly Phlebotomus perniciosus to enhance its immunity against Leishmania infantum, the cause of visceral leishmaniasis. By manipulating hormonal pathways and gut microbiota, the project aims to block the parasite's development within the vector, pot…
Vector-borne diseases create considerable risks to human health.
Leishmaniases are a group of neglected vector-borne diseases caused by protists parasites from the Leishmania genus.
Approximately 350 million people around the world are at risk of being infected with Leishmania, and clinical manifestations in humans vary from cutaneous to visceral types.
Leishmania is transmitted to humans by hematophagous female sand flies (Diptera, Psychodidae, Phlebotominae).
Here we focus on Phlebotomus perni…
UNIVERZITA KARLOVA
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