CORDIS Project
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This project investigates the mechanisms of neonatal seizures and their long-term effects on health. By targeting the P2X7 receptor, the research aims to develop new diagnostic and therapeutic strategies to improve outcomes for newborns at risk of seizures.
Newborns are predisposed to an increased risk of developing seizures following brain injury higher than in any other moment in a person’s life.
Data from experimental models and patients suggest seizures in neonates may cause increased mortality and a higher risk of adverse neurological outcomes including cerebral palsy, developmental delay and intellectual disability.
Consequently, the long-term health costs associated with seizures and neonatal brain damage are very high.
To date, both diagnos…
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