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The NeMatrix project aims to automate the culture and analysis of the roundworm Caenorhabditis elegans for drug screening. By developing a microfluidic platform, it seeks to enhance reproducibility and throughput in pre-clinical testing using alternative model organisms.
Alternative model organisms, such as worms or flies, are getting increasingly popular in the drug discovery field, since they are proving to be suitable for replacing mammals for several aspects of the screening tests in the pre-clinical phase.
In this context, one of the most interesting models is a roundworm species, named Caenorhabditis elegans.
Its microscopic size, however, hinders its actual use in the field, since the protocols for its maintenance and study still completely rely on manual…
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
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