CORDIS Project
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This project focuses on advancing organocatalytic technology by designing thiol-based catalysts that mimic the function of certain enzymes involved in the oxidation and reduction of aldehydes. The goal is to create efficient catalysts for synthesizing valuable chemical compounds under mild conditions.
The primary aim of this project is to substantially expand the frontiers of current benchmark organocatalytic technology by the design, preparation and evaluation of the first class of thiol-based nucleophilic catalyst capable of emulating the action of NAD+-dependant enzymes such as aldehyde dehydrogenases, which promote the chemoselective oxidation/reduction of aldehyde substrates under mild conditions in aqueous media.
The proposed artificial enzymes are designed biomimetically (in the true s…
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
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