CORDIS Project
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This project aims to develop a novel method using the Sodalis glossinidius bacterium to deliver targeted antibodies that disrupt the interaction between the tsetse fly and the Trypanosoma brucei parasite. The goal is to create a tsetse fly resistant to this parasite, which could have implications for controlling diseas…
The tsetse fly (Glossina spp.) salivary gland is the final micro-environment where the Trypanosoma brucei parasites adhere and undergo a complex re-programming cycle resulting in an end stage that is re-programmed to continue its life cycle in a new mammalian host.
The molecular parasite-vector communications that orchestrate this trypanosome development in tsetse fly salivary glands remain unknown mainly due to the limited availability of experimental tools for functional research.
We hypothes…
INSTITUUT VOOR TROPISCHE GENEESKUNDE
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