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The NANOLIGO project investigates a new method for synthesizing oligonucleotides using a technology called Nanostar Sieving. This approach aims to significantly reduce production costs and increase capacity for RNA-based therapies, making them more accessible to patients.
Since the Nobel Prize winning discovery of small interfering RNA its specificity and selectivity have driven the pharmaceutical industry to design 15- to 25-mer oligonucleotide analogues as a new class of drugs.
These offer exciting new therapeutic possibilities for example in rare diseases, but also large patient population indications including cardiovascular disease, and viral pandemics such as Covid-19.
However, the high cost and limited scalability of manufacturing these complex polymeric m…
EXACTMER LIMITED
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