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NanoACATre aims to develop innovative nanomaterials for treating hepatic fibrosis by enhancing cholesterol management in liver cells. The project focuses on creating Single Enzyme Nanogels to prevent liver cell activation and associated complications, contributing to advancements in nanomedicine and liver disease treat…
Hepatic fibrosis is a dynamic process characterized by the progressive replacement of functional liver tissue by an extracellular matrix rich in highly cross-linked collagen, with hepatic stellate cells being the main actors of this process.
NanoACATre, intended for the treatment for hepatic fibrosis based on augmenting intracellular Acyl-CoA:Cholesterol Acyltransferase (ACAT) in hepatic stellate cells, brings together a talented researcher (Dr.
Andoni Rodriguez-Abetxuko), with a background in n…
AARHUS UNIVERSITET
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