CORDIS Project
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This project investigates the molecular mechanisms of myoblast fusion, essential for muscle development and repair. It employs advanced imaging techniques to visualize the dynamic changes in cell membranes during the fusion process.
Cell-to-cell fusion is a ubiquitous phenomenon essential for the physiological function of numerous tissues. A striking example is the fusion of myoblasts to form multinucleated myofibers during skeletal muscle development and regeneration.
During myoblast fusion, membrane architecture must be radically remodeled.
Yet, how membrane remodeling occurs on the molecular level is poorly understood as, until now, there was no approach available for visualizing dynamic changes in the cellular ultrastru…
WEIZMANN INSTITUTE OF SCIENCE
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