CORDIS Project
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This project explores the role of specialized ribosomes in the myelination of glial cells, which is crucial for neuronal health. It aims to uncover how translation control affects myelin production and its implications for neurological disorders.
The myelin sheath is essential for neuronal function and health: myelinating glial cells speed up propagation of axonal potentials, fuel the energetic demands and regulate the ionic environment of neurons.
Lesions to the myelin sheath thus result in devastating neurological disorders that include multiple sclerosis, diabetic neuropathy and Charcot-Marie-Tooth disease.
Myelination involves a striking expansion of the glial cell membrane that relies on an exceptional increase in protein and lipid…
UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
UNIVERSIDAD DE SANTIAGO DE COMPOSTELA
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