CORDIS Project
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This project investigates how Mycobacterium tuberculosis and Mycobacterium abscessus adapt their central metabolism to varying metal availability, particularly iron and manganese. By utilizing proteomics and metabolomics, the research aims to uncover the relationship between metal homeostasis and bacterial metabolism,…
I aim to define how Mycobacterium tuberculosis (Mtb) and Mycobacterium abscessus (Mabs) have adapted their central metabolism (CM) to variation of metals availability.
Bacterial nutrition is a fundamental aspect of pathogenesis.
While the host environment is in principle nutrient-rich, hosts have evolved strategies to interfere with nutrient-acquisition by pathogens.
Pathogens, in turn, have developed mechanisms to circumvent these restrictions.
The ability to adapt to nutrient availability driv…
UNIVERSITA DEGLI STUDI DI PADOVA
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