CORDIS Project
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This research focuses on understanding the origins and rates of mutations in cells, particularly during sperm development and across different primate species. It aims to uncover the mechanisms that influence mutation rates and their evolutionary implications.
As individuals age, mutations accumulate inexorably in their cells, playing a key role in evolution, ageing, and disease.
Despite their importance, we still have a poor understanding of how mutations originate, or why some cells accumulate more mutations than others.
This proposal aims to address these fundamental questions by examining two axes of mutation rate variation: among cell types and across species.In Aim 1, we will decode the rules of germline mutation during mammalian spermatogenesis…
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
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CONSORCIO PARA LA EXPLOTACION DEL CENTRO NACIONAL DE ANALISIS GENOMICO
Spain, Barcelona
Type: Research institute
Activity type: Research Organisations
SME: No
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