CORDIS Project
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This project investigates the role of skeletal muscle in the progression of amyotrophic lateral sclerosis (ALS). By examining the effects of mutant proteins in muscle tissue, it aims to uncover new therapeutic targets that could improve treatment strategies for ALS patients.
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by motor neuron degeneration that leads to progressive muscle atrophy.
Currently only a few FDA-approved drugs are available for ALS, which merely extend patients’ life by a few months.
Thus, there is an urgent need for new and more effective disease-modifying treatments.
Although ALS is characterized by selective motor neuron degeneration, extensive evidence indicates that other cell types contribute to both…
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