CORDIS Project
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The project develops a new DNA amplification method called SPEX, which enhances the accuracy of genetic analysis from degraded samples in various fields like forensics and archaeology. By reducing errors in genotyping, it aims to improve the reliability of data from ancient and marginal specimens.
Traces of surviving degraded DNA in marginal clinical, forensic, archaeological, and environmental samples are generally amplified by PCR, which can often produce highly-skewed product distributions dominated by non-authentic sequences (due to DNA damage and PCR-generated artefacts).
The applicant has developed the SPEX amplification methodology, an alternative to PCR which has generated sequence data of unprecedented accuracy from specimens up to 60,000 years old. SPEX creates first-generation…
MINISTRY OF THE PRESIDENCY, JUSTICE AND RELATIONS WITH THE COURTS
MINISTERIO DE LA PRESIDENCIA, JUSTICIA Y RELACIONES CON LAS CORTES
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