CORDIS Project
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This project investigates the role of mucus systems in the intestine and lung as a defense mechanism against pathogens. It aims to understand how mucus layers function and their implications for diseases like ulcerative colitis and cystic fibrosis.
The overall aim of this proposal is to explain how the mucus systems of the intestine and lung act as a first innate immune defense line to protect our mucosal surfaces.
Mucins are of highly glycosylated proteins that build the mucus skeleton.We previously discovered that there are two mucus layers in the colon.
The inner mucus layer built around the MUC2 mucin is attached and impenetrable to bacteria, thus separating the intestinal bacteria from the epithelial cells.
However, how the dynamic co…
UGOT - GOETEBORGS UNIVERSITET/UNIVERSITY OF GOTHENBURG
GOETEBORGS UNIVERSITET
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