CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This research project focuses on understanding the mechanistic target of rapamycin (mTOR) signaling pathways, which are crucial for cell growth and proliferation. By determining the structures of mTOR complexes through X-ray crystallography, it aims to provide insights into their regulation and implications for human d…
Cell growth and proliferation are fundamental processes whereby organisms accumulate mass and are therefore tightly regulated.
Regulation is achieved by a complex network of signaling pathways responding to various environmental cues. A crucial nutrient and energy-sensitive pathway is centered on the Serine/Threonine kinase mechanistic target of rapamycin (mTOR).
In the cell, mTOR interacts with several proteins to form two multi-subunit signaling complexes: mTORC1 and mTORC2. mTORC1 responds to…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
