CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project aims to identify enzymes that can reverse the modification caused by the ubiquitin-related modifier 1, which plays a role in protein regulation and stress response. The research will enhance understanding of cellular processes and potential therapeutic targets.
Ubiquitin-related modifier 1 (Urm1) is known for its dual role as sulfur carrier protein (SCP) in tRNA thiolation and as an ubiquitin-like protein (UBL) that leads to an oxidant-induced posttranslational protein modification (PTM).
We recently, managed to recapitulate the Urm1-conjugation reaction for various targets in vitro and characterize the underlying molecular principles.
In most ubiquitin (Ub) and ubiquitin-like- conjugation systems, the active removal of the PTM constitutes a key featur…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
