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The MotionPicture project aims to develop an advanced optical microscopy platform to measure molecular dynamics and local viscosity in live cells. By combining fluorescence and Brillouin microscopy, it seeks to provide detailed insights into biomolecular interactions and dynamics.
Measuring the molecular dynamics and interactions of biomolecules in live cells is crucial for understanding cellular mechanisms.
While recent advances in super-resolution fluorescence microscopy have enabled molecular-level resolution in fixed samples, capturing dynamics in live cells remains a major challenge.
Conventional methods for studying molecular dynamics struggle with high fluorophore concentrations, photobleaching, and the need for extensive prior knowledge about the setup and sample.…
FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
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