CORDIS Project
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This project investigates how mechanical forces influence the development of different cell types in the C. elegans embryo. It aims to understand the mechanisms of mechanotransduction and their implications for medical applications, particularly in wound healing and cancer.
The importance of mechanical forces in biology is well accepted, yet an integrated view of their mode of action in vivo is lacking.
We intend to characterize in-depth the physical forces and cellular processes that coordinate the morphogenesis of different cell types contributing to an organ, taking the C. elegans embryo as a paradigm.We will achieve this by pursuing three axes:1.Building on our discovery of a hemidesmosome-based mechanotransduction pathway that operates between contracting musc…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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France, Illkirch Graffenstaden
Type: Research institute
Activity type: Research Organisations
SME: No
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