CORDIS Project
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This project investigates how the accumulation of gamma-aminobutyric acid (GABA) in Listeria monocytogenes can protect the bacteria from acidic environments. It aims to understand the mechanisms behind GABA production and its potential role in enhancing the organism's survival under stress conditions.
In previous work performed by Dr.
Karatzas it has been demonstrated that the presence of glutamate does not confer any acid resistance to L. monocytogenes grown in DM.
This is due to the absence of any GABA export in this medium even if glutamate is present.
Furthermore, L. monocytogenes accumulates high levels of intracellular GABA when challenged with HCl in both rich media like BHI and DM.
This accumulation of GABA intracellularly suggests that this response might protect cells under acidic…
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Ireland, Galway
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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