CORDIS Project
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This project focuses on understanding the signaling pathways involved in inflammatory diseases, particularly autoimmune conditions like rheumatoid arthritis. It employs genetically modified mice to explore the role of specific signaling molecules in inflammation and tissue damage.
Inflammatory diseases are highly prevalent, often chronic diseases that cause diminished quality of life and are connected with major causes of death in Western societies.
Despite their societal impact, their pathomechanism is incompletely understood, hindering development of novel therapeutic strategies.
In particular, little is known about the intracellular signal transduction processes involved in the tissue destruction phase of aggressive autoimmune diseases such as rheumatoid arthritis.
The…
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