CORDIS Project
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This project focuses on understanding and enhancing the potential of a novel type of neural stem cells derived from human embryonic stem cells. By investigating their growth requirements and signaling pathways, the goal is to develop strategies for expanding these cells in vitro, which could significantly impact regene…
Neural stem cells (NSCs) can propagate in vitro while retaining ability to differentiate into neurons, astrocytes and oligodendrocytes.
However, because of the nature of their developmental progression, NSCs isolated at different developmental stages or regions exhibit remarkable differences in their ability to yield specific neuron types.
Specifically, NSCs grown in vitro rapidly lose access to the full neuronal spectrum.
Limited NSC potential is one of the major impediments for applications in…
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