CORDIS Project
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This project aims to develop new anti-inflammatory treatments by targeting the NLRP3 inflammasome, a key player in various inflammatory diseases. By repositioning existing drugs, the project seeks to create effective therapies with lower costs and fewer side effects.
Although the number of anti-inflammatory drugs has increased during the past decade, there is still an urgent need to develop novel alternatives that overcome limitations of current treatments.
The most used therapies, such as non-steroidal anti-inflammatory drugs, non-analgesic anti-inflammatory drugs or colchicine, often present severe side-effects.
In addition, in recent years biologicals have appeared, but they are extremely expensive.
Therefore, novel therapeutic approaches with lower toxic…
UNIVERSITA DEGLI STUDI DI PADOVA
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