CORDIS Project
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This project aims to understand the genetic and environmental factors contributing to melanoma development due to ultraviolet radiation exposure. Using mouse models, it investigates how these factors influence cancer progression and seeks to improve patient stratification and public health strategies.
Melanoma incidence continues to increase across Europe and compared to other cancers, it disproportionately affects young people, causing a significant loss in life-years in those affected.
Ultraviolet radiation (UVR) is the only environmental risk factor in melanoma, but the underlying genetic constitution of the individual also plays an important role.
However, our knowledge of the gene-gene and gene-environment interactions in melanomagenesis is still very limited and here we will use various…
THE UNIVERSITY OF MANCHESTER
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