CORDIS Project
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This project focuses on understanding the mechanisms behind the formation of autophagosomes, which are essential for cellular recycling and degradation processes. By studying membrane dynamics and protein interactions, the research aims to provide insights into autophagy and its role in cellular health.
During autophagy initially small double membrane-bound structures expand and adopt cup-like shapes.
These cup-shaped structures fuse at their rims to give rise to autophagosomes within which cytoplasmic material is enclosed.
Subsequently autophagosomes fuse with endosomes and lysosomes and the content and the inner membrane are degraded.
Autophagy serves to recycle essential building blocks during starvation, to degrade damaged organelles, to clear cells of protein aggregates and to kill intrace…
UNIVERSITAT WIEN
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