CORDIS Project
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This project focuses on the Type VI Secretion System in bacteria, aiming to explore its potential as a novel antibacterial platform. By studying specific proteins called MIX-effectors, it seeks to develop new strategies to combat antibiotic-resistant infections.
Bacteria use various mechanisms to combat competitors and colonize new niches.
The Type VI Secretion System (T6SS), a contact-dependent protein delivery apparatus, is a widespread, recently discovered machine used by Gram-negative bacteria to target competitors.
Its toxicity is mediated by secreted proteins called effectors, yet the identity of many effectors, the mechanism of secretion of different effector classes, and their toxic activities remain largely unknown. I recently uncovered a wides…
TEL AVIV UNIVERSITY
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