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The MitoRNA project aims to enhance our understanding of mitochondrial gene expression by investigating the RNA life cycle and its coupling to transcription and translation. Using advanced structural biology techniques, it seeks to reveal the molecular mechanisms underlying mitochondrial RNA metabolism, which is crucia…
Mitochondria maintain an organellar genome that encodes for subunits of the respiratory chain.
Its coordinated expression is essential for eukaryotic life, and defects in this process lead to severe disease in humans.
Mitochondrial gene expression is carried out by unique dedicated molecular machineries, but the underlying molecular mechanisms remain poorly characterized.
During my previous work as a PhD student and Project Leader, I provided the structural basis of human mitochondrial transcrip…
UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS
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