CORDIS Project
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This project investigates the role of metabolism in cardiac injury during myocardial infarction, focusing on the protein Optic Atrophy 1 and its impact on mitochondrial structure and function. The research aims to uncover mechanisms that could lead to new therapeutic strategies for preventing heart failure and recurren…
Every year 15.9 million people worldwide suffer a myocardial infarction (MI) causing sudden death in some individuals and predisposing survivors to recurrent MI’s and heart failure (HF), making ischemic heart disease the greatest contributor to human mortality.
Research has uncovered molecular mechanisms that contribute to cellular demise during ischemic heart disease, however, to date there is no effective molecularly designed therapeutic.
Recent studies implicate metabolism in ischemic cardiac…
UNIVERSITA DEGLI STUDI DI PADOVA
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