CORDIS Project
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This project aims to develop artificial mitochondria to address mitochondrial diseases by creating energy-producing systems that mimic natural mitochondria. These artificial structures will be designed to enhance ATP synthesis and potentially serve as vehicles for gene therapy, targeting cells to improve health outcome…
Mitochondria are cell organelles that provide the energetic requirements of the body.
The majority of cellular ATP is produced by the membrane protein ATP synthase through a proton gradient across the mitochondrial inner membrane.
Alterations in ATP synthase biogenesis can result in severe mitochondrial diseases affecting tissues with high energy requirements as brain and muscles.
Mitochondrial diseases affect approximately 20 million people in the EU, causing 35 % of deaths during the first yea…
UNIVERSIDAD COMPLUTENSE DE MADRID
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