CORDIS Project
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This project investigates how mitochondria communicate with the plasma membrane to transport Coenzyme Q, a crucial lipid for cellular metabolism. It aims to understand mitochondrial strategies in preventing ferroptosis, a type of cell death, and explores potential therapeutic targets for diseases linked to mitochondria…
Mitochondria serve as the epicenter of cellular metabolism.
Their dynamic communication with other compartments within the cell ensures proper cellular function.
My recent work reveals how mitochondria communicate with the plasma membrane (PM) to transport a redox-active lipid Coenzyme Q (Ubiquinone or CoQ).
This communication is crucial for inhibiting a form of iron-mediated cell death called ferroptosis.
Notably, CoQ is exclusively synthesized within the mitochondria and plays a pivotal role i…
HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
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