CORDIS Project
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This project focuses on modeling the structure and mechanisms of sister chromatids cohesion and their organization during chromosome replication. Utilizing a novel technique, it aims to analyze chromatid interactions and understand their implications for cellular functions, including gene expression and DNA repair.
The proposed project aims at modeling the structure and mechanisms of sister chromatids cohesion, and how it coordinates with intra-chromatid organization to shape replicated human chromosomes and support fundamental biological mechanisms.
Indeed, sister chromatids organisation and its contribution to cellular functions remained elusive due to the lack of appropriate techniques able to distinguish the identical sequences of sister chromatids.
The recent development of sister-chromatid-sensitive…
INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH
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