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MiST-MS aims to uncover the role of glial cells in chronic inflammation related to multiple sclerosis. The project utilizes advanced genetic techniques to explore how these cells contribute to brain aging and identify potential therapeutic targets.
Shifting from the traditional focus on central nervous system-targeting lymphocytes, MiST-MS posits that glial responses, particularly cellular senescence, are required to compartmentalized self-sustaining chronic inflammation in multiple sclerosis (MS) and related long-term clinical outcomes, including disability.
MiST-MS is specifically designed to address the urgent need to identify new therapeutic targets to halt MS clinical progression through two interconnected research lines.The project w…
HUMANITAS UNIVERSITY
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