CORDIS Project
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This project investigates the regulation of microRNAs in the roundworm Caenorhabditis elegans, focusing on their turnover mechanisms and the impact on development and disease. By employing biochemical and genomic techniques, the research aims to clarify the roles of these small gene regulators under physiological condi…
MicroRNAs (miRNAs) are a novel class of genes, accounting for >1% of genes in a typical animal genome.
They constitute an important layer of gene regulation that affects diverse processes such as cell differentiation, apoptosis, and metabolism.
Despite such critical roles, deciphering the mechanism of action of miRNAs has been difficult, leading to multiple, partially contradictory, models of miRNA activity.
Moreover, adding an additional layer of complexity, it is now emerging that miRNA activi…
FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION
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