CORDIS Project
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This project aims to uncover the role of microRNAs in the function of pancreatic beta cells, which are crucial for insulin secretion. It investigates how these small RNA molecules contribute to the development of Type 2 diabetes and explores their potential as therapeutic targets.
Type 2 diabetes mellitus (T2DM) is caused by a relative inability of the endocrine pancreas to meet the increasing metabolic demands of insulin resistance associated with obesity and ageing.
Impaired insulin secretion is an early and critical step in the pathogenesis of type 2 diabetes, but the underlying mechanism of ß-cell loss and dysfunction in T2DM are incompletely understood.
Recent studies have indicated a role for several microRNAs (miRNAs), a recently discovered class of evolutionarily…
UNIVERSITAIR MEDISCH CENTRUM GRONINGEN
ACADEMISCH ZIEKENHUIS GRONINGEN
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