CORDIS Project
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This project investigates how the RNA-binding protein RBM38 influences the cellular stress response by regulating microRNA activity on specific messenger RNAs. The goal is to understand the molecular mechanisms involved, which could lead to advancements in cancer treatment and molecular medicine.
The aim of the research activities detailed in this proposal is to understand how the RNA-binding protein RBM38 mediates the cellular stress response —the series of cellular events triggered by diverse harmful factors to restore cellular homeostasis— by modulating the activity of microRNAs on specific targets.
Our objective is to determine the molecular mechanism by which RBM38 interferes with the binding of miRNAs on a selection of messenger RNAs that are targets of the tumor suppressor p53, a…
MEDICAL RESEARCH COUNCIL
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