CORDIS Project
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This project develops a novel assay system using nanoscale DNA origami arrays for the detection and quantification of microRNAs in breast cancer. The approach aims to enhance the sensitivity and multiplexing capabilities of current detection methods, potentially improving early cancer diagnosis and monitoring.
MicroRNAs (miRNAs) are potential biomarkers for cancer diagnosis, prognosis and treatment monitoring.
Specific detection and absolute quantification of miRNAs is of clinical relevance for early cancer detection and monitoring progression.
The currently available techniques for miRNA detection based on DNA amplification are limited by lack of absolute quantification, low multiplexing capacity and time consumption.
Here, I propose to develop a miRNA assay system based on self-assembled nanoscale D…
UNIVERSITE DE FRIBOURG
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